Review



usp7 dna construct  (Addgene inc)


Bioz Verified Symbol Addgene inc is a verified supplier  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 93
      Buy from Supplier

    Structured Review

    Addgene inc usp7 dna construct
    Clinical characteristics of enrolled HCC patients.
    Usp7 Dna Construct, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 18 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/usp7 dna construct/product/Addgene inc
    Average 93 stars, based on 18 article reviews
    usp7 dna construct - by Bioz Stars, 2026-05
    93/100 stars

    Images

    1) Product Images from "Clinical Significance of Ubiquitin Specific Protease 7 (USP7) in Predicting Prognosis of Hepatocellular Carcinoma and its Functional Mechanisms"

    Article Title: Clinical Significance of Ubiquitin Specific Protease 7 (USP7) in Predicting Prognosis of Hepatocellular Carcinoma and its Functional Mechanisms

    Journal: Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

    doi: 10.12659/MSM.909368

    Clinical characteristics of enrolled HCC patients.
    Figure Legend Snippet: Clinical characteristics of enrolled HCC patients.

    Techniques Used:

    USP7 is upregulated in HCC tumor tissues. ( A ) RT-PCR results showed that the RNA level of USP7 was increased in HCC tumor tissues than that in adjacent normal liver tissues, and was positively correlated with the TNM stage. ( B ) Representative IHC result showed the negative protein expression of USP7 in normal liver tissues. ( C ) Representative IHC result showed the high protein level of USP7 in HCC tissues, which predominately located in the nucleus. ( D ) Statistical analysis of IHC scores in normal liver tissues and HCC tissues showed a significantly higher USP7 protein level in tumor tissues. Magnification: ×400. Data was presented as mean ±SD. * P<0.05 by Student’s t-test.
    Figure Legend Snippet: USP7 is upregulated in HCC tumor tissues. ( A ) RT-PCR results showed that the RNA level of USP7 was increased in HCC tumor tissues than that in adjacent normal liver tissues, and was positively correlated with the TNM stage. ( B ) Representative IHC result showed the negative protein expression of USP7 in normal liver tissues. ( C ) Representative IHC result showed the high protein level of USP7 in HCC tissues, which predominately located in the nucleus. ( D ) Statistical analysis of IHC scores in normal liver tissues and HCC tissues showed a significantly higher USP7 protein level in tumor tissues. Magnification: ×400. Data was presented as mean ±SD. * P<0.05 by Student’s t-test.

    Techniques Used: Reverse Transcription Polymerase Chain Reaction, Expressing

    Kaplan-Meir survival curves of HCC patients. Overall survival analyses were conducted by Kaplan-Meir method and compared by log-rank test according to patients’ age ( A ), gender ( B ), tumor number ( C ), tumor size ( D ), TNM stage ( E ), and USP7 protein level ( F ). * P<0.05 by log-rank test.
    Figure Legend Snippet: Kaplan-Meir survival curves of HCC patients. Overall survival analyses were conducted by Kaplan-Meir method and compared by log-rank test according to patients’ age ( A ), gender ( B ), tumor number ( C ), tumor size ( D ), TNM stage ( E ), and USP7 protein level ( F ). * P<0.05 by log-rank test.

    Techniques Used:

    Kaplan-Meier overall survival of enrolled HCC patients.
    Figure Legend Snippet: Kaplan-Meier overall survival of enrolled HCC patients.

    Techniques Used: Expressing

    Cox multivariate analysis of enrolled HCC patients.
    Figure Legend Snippet: Cox multivariate analysis of enrolled HCC patients.

    Techniques Used: Expressing

    USP7 enhances tumor cell proliferation, migration, and invasion. The proliferation curves of HCC cells were plotted by MTT assays, which showed that USP7 can enhance the cell viability in both Hep3B ( A ) and Huh7 ( B ) cells. Wound-healing assays were performed to evaluate the migration capacity of HCC cells, indicating a promoting role of USP7 on cell migration ( C, D ). The invasion process of tumor cells was monitored by Matrigel-transwell assay, demonstrating that USP7-overexpression enhanced cell invasion, while USP7-knockdown suppressed tumor invasion ( E, F ). Data was presented as mean ±SD. * P<0.05 by Student’s t-test.
    Figure Legend Snippet: USP7 enhances tumor cell proliferation, migration, and invasion. The proliferation curves of HCC cells were plotted by MTT assays, which showed that USP7 can enhance the cell viability in both Hep3B ( A ) and Huh7 ( B ) cells. Wound-healing assays were performed to evaluate the migration capacity of HCC cells, indicating a promoting role of USP7 on cell migration ( C, D ). The invasion process of tumor cells was monitored by Matrigel-transwell assay, demonstrating that USP7-overexpression enhanced cell invasion, while USP7-knockdown suppressed tumor invasion ( E, F ). Data was presented as mean ±SD. * P<0.05 by Student’s t-test.

    Techniques Used: Migration, Transwell Assay, Over Expression, Knockdown



    Similar Products

    usp7 dna construct  (Addgene inc)
    93
    Addgene inc usp7 dna construct
    Clinical characteristics of enrolled HCC patients.
    Usp7 Dna Construct, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/usp7 dna construct/product/Addgene inc
    Average 93 stars, based on 1 article reviews
    usp7 dna construct - by Bioz Stars, 2026-05
    93/100 stars
    		  Buy from Supplier

    Image Search Results


    Clinical characteristics of enrolled HCC patients.

    Journal: Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

    Article Title: Clinical Significance of Ubiquitin Specific Protease 7 (USP7) in Predicting Prognosis of Hepatocellular Carcinoma and its Functional Mechanisms

    doi: 10.12659/MSM.909368

    Figure Lengend Snippet: Clinical characteristics of enrolled HCC patients.

    Article Snippet: The USP7 DNA construct was purchased from Addgene ( https://www.addgene.org/16655/ ).

    Techniques:

    USP7 is upregulated in HCC tumor tissues. ( A ) RT-PCR results showed that the RNA level of USP7 was increased in HCC tumor tissues than that in adjacent normal liver tissues, and was positively correlated with the TNM stage. ( B ) Representative IHC result showed the negative protein expression of USP7 in normal liver tissues. ( C ) Representative IHC result showed the high protein level of USP7 in HCC tissues, which predominately located in the nucleus. ( D ) Statistical analysis of IHC scores in normal liver tissues and HCC tissues showed a significantly higher USP7 protein level in tumor tissues. Magnification: ×400. Data was presented as mean ±SD. * P<0.05 by Student’s t-test.

    Journal: Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

    Article Title: Clinical Significance of Ubiquitin Specific Protease 7 (USP7) in Predicting Prognosis of Hepatocellular Carcinoma and its Functional Mechanisms

    doi: 10.12659/MSM.909368

    Figure Lengend Snippet: USP7 is upregulated in HCC tumor tissues. ( A ) RT-PCR results showed that the RNA level of USP7 was increased in HCC tumor tissues than that in adjacent normal liver tissues, and was positively correlated with the TNM stage. ( B ) Representative IHC result showed the negative protein expression of USP7 in normal liver tissues. ( C ) Representative IHC result showed the high protein level of USP7 in HCC tissues, which predominately located in the nucleus. ( D ) Statistical analysis of IHC scores in normal liver tissues and HCC tissues showed a significantly higher USP7 protein level in tumor tissues. Magnification: ×400. Data was presented as mean ±SD. * P<0.05 by Student’s t-test.

    Article Snippet: The USP7 DNA construct was purchased from Addgene ( https://www.addgene.org/16655/ ).

    Techniques: Reverse Transcription Polymerase Chain Reaction, Expressing

    Kaplan-Meir survival curves of HCC patients. Overall survival analyses were conducted by Kaplan-Meir method and compared by log-rank test according to patients’ age ( A ), gender ( B ), tumor number ( C ), tumor size ( D ), TNM stage ( E ), and USP7 protein level ( F ). * P<0.05 by log-rank test.

    Journal: Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

    Article Title: Clinical Significance of Ubiquitin Specific Protease 7 (USP7) in Predicting Prognosis of Hepatocellular Carcinoma and its Functional Mechanisms

    doi: 10.12659/MSM.909368

    Figure Lengend Snippet: Kaplan-Meir survival curves of HCC patients. Overall survival analyses were conducted by Kaplan-Meir method and compared by log-rank test according to patients’ age ( A ), gender ( B ), tumor number ( C ), tumor size ( D ), TNM stage ( E ), and USP7 protein level ( F ). * P<0.05 by log-rank test.

    Article Snippet: The USP7 DNA construct was purchased from Addgene ( https://www.addgene.org/16655/ ).

    Techniques:

    Kaplan-Meier overall survival of enrolled HCC patients.

    Journal: Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

    Article Title: Clinical Significance of Ubiquitin Specific Protease 7 (USP7) in Predicting Prognosis of Hepatocellular Carcinoma and its Functional Mechanisms

    doi: 10.12659/MSM.909368

    Figure Lengend Snippet: Kaplan-Meier overall survival of enrolled HCC patients.

    Article Snippet: The USP7 DNA construct was purchased from Addgene ( https://www.addgene.org/16655/ ).

    Techniques: Expressing

    Cox multivariate analysis of enrolled HCC patients.

    Journal: Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

    Article Title: Clinical Significance of Ubiquitin Specific Protease 7 (USP7) in Predicting Prognosis of Hepatocellular Carcinoma and its Functional Mechanisms

    doi: 10.12659/MSM.909368

    Figure Lengend Snippet: Cox multivariate analysis of enrolled HCC patients.

    Article Snippet: The USP7 DNA construct was purchased from Addgene ( https://www.addgene.org/16655/ ).

    Techniques: Expressing

    USP7 enhances tumor cell proliferation, migration, and invasion. The proliferation curves of HCC cells were plotted by MTT assays, which showed that USP7 can enhance the cell viability in both Hep3B ( A ) and Huh7 ( B ) cells. Wound-healing assays were performed to evaluate the migration capacity of HCC cells, indicating a promoting role of USP7 on cell migration ( C, D ). The invasion process of tumor cells was monitored by Matrigel-transwell assay, demonstrating that USP7-overexpression enhanced cell invasion, while USP7-knockdown suppressed tumor invasion ( E, F ). Data was presented as mean ±SD. * P<0.05 by Student’s t-test.

    Journal: Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

    Article Title: Clinical Significance of Ubiquitin Specific Protease 7 (USP7) in Predicting Prognosis of Hepatocellular Carcinoma and its Functional Mechanisms

    doi: 10.12659/MSM.909368

    Figure Lengend Snippet: USP7 enhances tumor cell proliferation, migration, and invasion. The proliferation curves of HCC cells were plotted by MTT assays, which showed that USP7 can enhance the cell viability in both Hep3B ( A ) and Huh7 ( B ) cells. Wound-healing assays were performed to evaluate the migration capacity of HCC cells, indicating a promoting role of USP7 on cell migration ( C, D ). The invasion process of tumor cells was monitored by Matrigel-transwell assay, demonstrating that USP7-overexpression enhanced cell invasion, while USP7-knockdown suppressed tumor invasion ( E, F ). Data was presented as mean ±SD. * P<0.05 by Student’s t-test.

    Article Snippet: The USP7 DNA construct was purchased from Addgene ( https://www.addgene.org/16655/ ).

    Techniques: Migration, Transwell Assay, Over Expression, Knockdown